The use of clotrimazole for lichen in adults and children

1

Tinea versicolor is a fungal disease, it begins due to the pathogens Malassezia furfur and Pityrpsporum orbiculare, the breeding site of which is the stratum corneum of the epidermis. Microscopic examination of the affected area of ​​the skin shows that the fungus is located in the epidermis in clusters in the form of complete curved threads. To change the situation for the better, doctors prescribe ointment for ringworm.

You can become infected with tinea versicolor if:

• have personal contact with a sick person (in most cases this is an inherited disease)
• use the patient’s personal hygiene items (dishes, bath accessories)
• visit changing rooms or fitting rooms designed for a huge number of people

Cloveit for lichen planus

Lichen planus: causes, symptoms and treatment Lichen planus is a very common skin disease that quickly becomes chronic.
In most cases, it is a companion to other diseases (gastritis, cirrhosis of the liver, duodenal or gastric ulcer). Symptoms manifest as flat rashes in the area of ​​the forearms, wrists and ankles. Can affect the mucous membranes of the oral cavity, as well as the nail plates. The disease is characterized by frequent and severe itching and burning in the areas of the rash. The rashes come in various forms and range in color from light pink to purple-red (see photo).

What it is?

Lichen planus in humans is a chronic multifactorial dermatosis that affects the skin, nails, and mucous membranes. It is distinguished by a long course and a variety of clinical manifestations, and most often affects elderly people.

Unlike other forms of lichen, lichen planus is not contagious and cannot be spread from person to person. A number of scientific studies have been devoted to the study of this dermatosis, but the exact cause of the disease has not yet been established.

Reasons for development

The true causes of lichen planus have not been discovered. Experts are inclined to believe that the pathological mechanism is triggered by the following factors:

1. The autointoxication factor occurs due to the accumulation of toxins in the body. A similar disorder occurs in arterial hypertension, cirrhosis and hepatitis, diabetes mellitus, gastritis and gastric ulcer. A biochemical analysis of the blood of shingles patients shows changes in liver samples.
2. The intoxication factor affects the body in a similar way to an allergic reaction developed as a result of treatment with certain medications. These are preparations of gold, aluminum, antimony, arsenic and iodine. Lichen lesions can also appear on the body as a result of taking antibiotics and anti-tuberculosis medications, quinine and its derivatives.
3. Viral-infectious, leading to increased cell division of the upper dermal level. Trying to fight back the negative influence of the factor, the immune system triggers the production of antibodies, which subsequently absorb their own beneficial cells. In Wilson's disease, these become epidermal cells.
4. The immunoallergic impetus for the development of the disease is considered the leading one among all theories and unites them, because each of them is based on failures of the body’s protective functions.
5. Neurogenic, provoking dermatosis after mental shock. Often, patients suffering from red lichen develop a variety of nervous system disorders. With neuritis, lichen elements form on the skin along the nerve branches.

How can you answer the question whether lichen ruber is contagious or not? Doctors do not have a unanimous opinion regarding the danger of Wilson's disease for others. Dermatosis can affect both members of the same family and the dermatologist himself, who takes the affected tissue for a biopsy.

Multiple episodes of infection of a doctor were not recorded, but a single case did occur in dermatological practice. The conclusion suggests itself is the following: in order to avoid the risk of catching an unnecessary sore, you should not allow close contact with a person covered with lichen spots.

Symptoms of lichen planus

The clinical picture of lichen planus (see photo) largely depends on the form of the disease, location and characteristics of the course of the disease. A typical symptom is the appearance of small, shiny, red papules on the skin that gradually enlarge to the size of a lentil grain.

The first lesions usually appear on the legs and arms in the joint area; after a few days, the rashes spread to other parts of the body. Papules are not prone to merging, have regular outlines and a slight depression in the center. Small papules can be grouped in a circle or form garlands and lines in which they fit tightly to each other, but do not merge into plaques. The appearance of rashes is accompanied by intense skin itching. The diameter of such formations can reach one centimeter.

Over time, the surface of the plaques becomes rough and covered with small gray scales. The papules themselves become burgundy or bluish in color. After the rash disappears, pigmented brown areas remain on the skin.

• When the mucous membrane of the mouth is affected, whitish shiny papules appear on the inner lateral surface, palate, back of the tongue, red border of the lips, and gums. They are localized in such a way that they resemble a grayish-white lace mesh. There is a feeling of tightness, burning, and pain in the mouth when eating hot or spicy food.
• If lichen affects the nails, then deformation of the nail plates is observed, they become lumpy, grooves and grooves appear on the surface, and the color changes. Nails break easily, crumble and become thin.

With the development of a severe, erosive-ulcerative form, severe pain appears when eating any food, and bleeding ulcers form on the oral mucosa. Lichen planus can manifest itself in different ways. There are several main forms of this disease. [adsen]

Forms and variants of the course of the disease

Lichen planus is divided into five types:

1. Bubble shape. Presents as blisters with serous or hemorrhagic exudate. In the first case, they are filled with a clear liquid containing less than 8% protein, in the second - with a liquid containing red blood cells. This is one of the rarest forms of lichen planus. Its lesions are localized on the legs and feet against the background of plaques, nodules and itching, or on their own.
2. Pointed shape. It occurs most often on the head. Ringworm affects the hair follicles, and in their place specific spikes are formed that protrude upward. After they disappear, a kind of scars remain on the head, looking like depressions.
3. Ring shape. It is characterized by the rapid growth of foci of inflammation, which simultaneously heal in the center. As a result, a ring-like lichen is obtained. There are also garland shapes, semicircular and arc.
4. Atrophic form. In the initial stages it has no special manifestations. However, after healing, seals remain at the site of the lesions. Such keratinized areas are most often found on the knee and elbow joints. When they appear on the head, partial baldness is observed.
5. Warty form. The growths look like warts located on red plaques. This type of lichen is usually located on the legs, is accompanied by severe itching and is difficult to treat.
6. Sclerosing form. Is the most rare. It differs in that it leads to atrophy of the skin or sclerotic thickening.

There are also three forms of lichen planus, the symptoms of which occur on the mucous membranes:

1. Erosive-ulcerative form. Causes the formation of irregularly shaped ulcers with a loose bottom.
2. Exudative-hyperemic. It is characterized by foci of inflammation of the mucous membranes, on which papules form. This type primarily affects the gums and inner lips and is characterized by burning and pain.
3. Hyperkeratic. It appears in the form of large plaques that rise greatly above the level of the mucosa.

In its course, lichen planus can be acute (lasts up to 1 month) or subacute (lasts up to 6 months) and long-term (more than 6 months).

Localization

Lichen planus differs significantly from other forms of this disease. As a rule, the inflammatory process manifests itself in the following places:

• joints and forearms in the flexion area;
• neck area;
• shin;
• external genitalia in men.

As for the mucous membrane, the infection manifests itself in the following places:

• mucous membrane of the genital organs;
• oral mucosa.

Pathology most often manifests itself in the mouth. At the initial stage of development, lichen planus symptoms resemble ordinary stomatitis. However, medications to treat stomatitis do not provide any relief.

Active ingredient and base of ointment and cream

Clotrimazole is the active ingredient of a large group of ointments and creams. The active ingredient is one of the first synthetic derivatives of the effective antifungal (antimycotic) drug imidazole. The percentage of clotrimazole in the ointment is 1% (1 g of active ingredient per 100 g of external agent).

Often in everyday life, medicinal creams and gels are called ointments. Soft dosage forms differ significantly in the composition of auxiliary ingredients. Russian-made ointments usually use Vaseline; creams contain water and alcohols. The bases are not the same, so the speed and depth of penetration of the active substance into the skin is different.

The auxiliary ingredients of the ointment form its base. These are Vaseline, wax emulsion, polysorbate-80, castor oil. This base provides a longer antimycotic effect. The downside of Vaseline is a greasy film on the skin, a “greenhouse” effect of the product in heat, in hot weather.

The content of the active ingredient in the cream for external use is 1 or 2%. This product is less greasy than ointment and does not stain linen and clothes much less. The cream is easier to distribute on the skin, but the depth of penetration and duration of action is slightly less compared to ointment.

Diagnostics

The symptoms of lichen planus are quite well expressed, but an accurate diagnosis can only be made after diagnostics. For example, skin rashes in the initial stage are similar to an allergic reaction. The symptoms of formations in the mouth resemble stomatitis. Therefore, an accurate diagnosis can be made only after conducting an instrumental research method.

Also, with the help of additional instrumental studies, it is possible to identify the cause of the development of the inflammatory process. To do this, a biopsy of the affected area of ​​skin is performed. In some cases, a general blood test is required.

Effect on the disease

Clotrimazole for lichen is a medicine from the imidazole group. It is widespread due to its spectrum of action, which covers many types of fungus:

• blastomycosis;
• molds;
• dermatophytes;
• dimorphic parasites;
• actinomycetes of the Nocardia family.

It has the following effect on pathogenic flora: The fungal cell, like all known in nature, is enclosed in a membrane.

Clotrimazole affects her specifically and disrupts her metabolic processes. As a result, the pathogenic flora is not able to develop further.

The drug also suppresses the main development processes in the fungal cell, which actually destroys the pathogenic flora on the skin.

Among other things, the ointment also copes well with bacteria and has antiseptic properties, promoting healing.

How to treat lichen ruber?

Treatment of this dermatosis in humans is always carried out in stages and in a comprehensive manner. The treatment plan may include the following drugs:

• means for normalizing tissue trophism;
• means to reduce the activity of the immune system (in severe cases);
• local ointments and other remedies;
• means to eliminate itching, stabilize the functioning of the nervous system and sleep.

In addition, to speed up recovery, methods of influencing the factors that provoke the disease are used:

• treatment of oral pathology;
• stress management;
• correction of previously prescribed medications;
• elimination of harmful factors at work;
• normalization of diet, etc.

Medicines are prescribed to patients in cases where there is a violation of their general health. The selection of the necessary funds depends on each clinical case. The following oral medications can be used to treat lichen planus:

• antihistamines: Tavegil, Zyrtec, Diazolin, Clemastine, Promethazine, Loratadine, Fenkarol, etc.;
• immunosuppressants: Cyclosporine A, Chloroquine, Hydroxychloroquine;
• systemic retinoids: Neotigazon, Acitretin, Tigazon, Isotretion, Etretinate;
• corticosteroids: Metipred, Prednisolone;
• antibiotics: Tetracycline, Metacycline, Doxycycline, Azithromycin, Sumamed, Roxithromycin;
• synthetic interferons: Ridostin, Neovir, Interferon-alpha 2B;
• vascular drugs to improve tissue trophism: Xanthinol, Trental, etc.;
• sleeping pills and sedatives: Phenazepam, Medazepam;
• vitamin preparations: Ascorbic acid, B vitamins, vitamin D.

In addition, the drug therapy plan may include drugs for the treatment of concomitant diseases: diabetes mellitus, neurosis, arterial hypertension, chronic inflammatory processes (for example, glossitis, stomatitis, etc.).

For local therapy of lichen planus, the following agents are used:

• non-hormonal anti-inflammatory ointments: Pimecrolimus, Tacrolimus;
• non-hormonal antiallergic ointments: Gistan, Fenistil;
• exfoliating ointments: Belosalik, Diprosalik;
• ointments to accelerate tissue regeneration: Solcoseryl;
• ointments based on corticosteroids: Cloveit, Flumethasone, Hydrocortisone, Betameson, Triamcinolone

Local remedies for the treatment of this dermatosis can be used either independently or in combination with each other. They can only be prescribed by a doctor who takes into account the form, severity and stage of the disease.

Analogues of the drug

The active substance of the ointment and cream was created a long time ago and has been well studied. External products based on clotrimazole are produced in many countries. Russian pharmaceutical companies usually use petroleum jelly and mineral oil as a base, which significantly reduces the cost of finished drugs.

Analogs for the active substance:

It happens that the antifungal agent is not effective. The way out of this situation is to change the drug to an analogue from the same drug group, which has a similar mechanism of action and indications. Instead of Clotrimazole ointment and cream, you can use group analogues. Antifungal ointments and creams:

Clotrimazole is part of the combination drug Candide B. The second component of this cream, the hormonal substance beclomethasone, has a strong anti-inflammatory and antiallergic effect. The cream is used to treat thrush, which is accompanied by pain and itching. The price of the drug is 430 rubles.

Folk remedies

There are many treatments for lichen planus that can be used at home. These include treatment with sea buckthorn oil, grated beets, and calendula.

1. Calendula is a popular and useful plant used in folk medicine. Alcohol tincture of calendula is effective in treatment. If desired, we either buy it or prepare it like this: add 10 grams of crushed calendula to alcohol (100 grams). Let it sit for several hours and use it as a lotion. This ointment option is also possible: calendula, ground into powder, mixed with 50 grams of petroleum jelly and infused.
2. Grated beets are good as a compress. Rub it on a grater and apply it to the infected area of ​​skin, wrapping it with a bandage. When the compress dries out, replace it with a new one. We repeat applications until the lichen disappears.
3. We make gauze lotions soaked in sea buckthorn oil and apply them to the affected areas for up to 60 minutes daily. You can take sea buckthorn oil orally for medicinal purposes - in the morning on an empty stomach with a dosage of 15 ml.

Contraindications

"Clotrimazole" is contraindicated for people with sensitive and delicate skin: it may leave minor burns. To make sure there are no contraindications, you need to apply the ointment to a healthy area of ​​skin and check the reaction after 2 hours. If there is no redness, then you can apply the cream. If there is, tablets are prescribed. Clotrimazole should not be used by young mothers while pregnant or breastfeeding. This can cause an allergic reaction in the baby and negatively affect his health, especially the appearance of his skin.

An allergic reaction to individual components of Clotrimazole is possible. In this case, the person cannot use the drug in any form. Other, similar antifungal medications are prescribed.

Prevention

Due to the variety of causes and many factors in the occurrence of lichen planus, a unified scheme for the prevention of the disease has not been developed.

Possible preventive measures:

1. Hardening.
2. Stress resistance.
3. Taking vitamins and minerals.
4. Strengthening the immune system.
5. Timely contact with specialists and treatment of emerging diseases.

Thus, correct diagnosis, rationally selected treatment methods, and compliance with preventive recommendations contribute to the rapid achievement of a positive result in eliminating lichen planus.

Reviews

We studied reviews available online. It should be noted that judging by them, this ointment does not help everyone equally, although for those whose diagnosis was clearly made by the doctor, based on all the test results, the treatment had a 100% positive effect.

Thus, you and I must understand that success in the treatment of lichen, with any selected drugs or traditional methods, depends entirely on the diagnosis.

For any known form of lichen, this is always to examine the sore spot with special lamps and scrape off the scales for further examination under a microscope.

It may also be necessary to sow a mushroom and grow the microflora a little, creating all the necessary conditions for this. Only in this way can one accurately answer the question about the cause of the disease and its causative agent.

I am attaching a video where a dermatologist talks in detail about this drug:

Forecast

In most cases, dermatosis responds well to treatment, and in mild forms it heals on its own. The pathology may recur after several years.

A severe course is observed with erosive forms of lichen planus. In such cases, dermatosis takes a long time to treat and recurs more often than other forms of this disease.

Reading time: 8 minutes. .1k. Published 09/10/2018 Updated 07/23/2019

Many parents are concerned about how to treat lichen planus? But in order to know treatment methods, you need to understand what the disease is.

What is lichen planus?

This health problem belongs to the group of systemic dermatoses, the most important associated factor of which is the formation of red papules on different parts of the epidermis. Lichen planus can appear on the skin, mucous membranes, and nails.

Causes of lichen

Lichen planus is very common, especially in children. Often appears on the spot:

• Injury
• Abrasions.
• Cuts.

Usually formed by:

• Stress.
• Strong feelings.
• While taking medications.

Let's celebrate! Lichen planus is not considered contagious. This is an autoimmune disease. But most people who get sick, they all suffer from hepatitis C.

Symptoms and forms of lichen

The first signs of the development of lichen planus are spots:

• On the arms and legs.
• In the area of ​​the joints.

They have a purple color. Then nodules appear that are very itchy. There is also a vesicular form. At this time, bubbles form on the body.

This form even occurs on the tongue or mucous membrane. This is very similar to common oral fungus. Therefore, special analyzes and studies are required.

The forms of lichen planus include:

Typical (most common):

• The presence of dense red papules, 2-3 mm in diameter, round, oval in shape.
• Normal condition and well-being.
• Papules have a scarlet tint.
• Mild peeling.

Hypertrophic (wart):

• Locations in the legs.
• Over time, the course of lichen planus plaques can merge into large areas.
• The diameter of the plaques is 4-7 cm.
• The papules have an uneven, warty surface, and the skin has a purple tint.
• There is intense itching.
• Lichen planus is quite difficult to treat, maybe even several years.

Atrophic:

• Plaques on the surface of the skin differ from the standard form by a slight retraction of the skin.
• The epidermis loses its color and elasticity.
• Lichen planus on the head and genitals.
• A few areas of damage are formed.

• The form arises and proceeds very quickly.
• Numerous rashes are not observed.
• The plaques are brown in color and often merge into large areas.
• Lichen planus spreads to the trunk, limbs, and face.

Erosive-ulcerative form:

• Lichen planus spreads to the cheeks, lips, and tongue mucosa.
• The patient swallows, chews, and develops an unpleasant odor from the mouth.
• High probability of infectious stomatitis and inflammation of the oral cavity.
• There is an increase in lymph nodes.

Pemphigoid (bubbly):

• It often manifests itself in those who have a history of chronic diseases of the cardiovascular system, gastrointestinal tract, kidneys, and suffer from frequent sore throats.
• Blisters with a dense covering appear on the injured areas, and the rash varies in size.
• On the mucous membranes of the mouth, the rash has a light, whitish tint and is up to 10 mm in size.
• With a long course of lichen planus, erosions form.
• In difficult situations, the disease can be aggravated by a fungal infection, viruses and bacteria are added.

What does lichen planus look like - photo

Effective treatment of lichen planus

Lichen planus becomes a chronic condition that is almost impossible to cure, especially if you approach it irresponsibly.

Effective ointments

Disinfecting ointments “Levomekol”, “Solcoseryl”, used 2 times a day until painful symptoms disappear. They speed up the recovery process and disinfect. Levomekol ointment costs from 40 to 80 rubles, Solcoseryl is offered at a price of 300 rubles. Allowed to be used at any age.

Folk remedies

Rinsing with infusions of string and celandine. Squeeze the juice of a fresh plant, mix with vodka in equal parts. Suitable for the treatment of lichen planus. Carry out the procedure 3 times a week, with breaks of 1 day. Can be used by patients of any age, contraindications – allergies.

Tincture of oak growths acts as a bactericidal agent. To do this, you need to infuse 50 g of oak galls in 300 ml of vodka for 7 days, process 2-3 times a day for 1 week. Suitable for infants.

Diet for lichen

It is imperative to carry out hardening procedures and those that help strengthen the immune system.

The patient should eat a lot of raw fruits and vegetables, and in the winter and autumn seasons it is worth taking vitamin complexes prescribed by the doctor. During this period, it is better to limit the consumption of the following products:

All products containing stabilizers, flavors and dyes that can increase the allergic reaction when lichen planus develops:

• Cakes, chocolate, pastries and flour products.
• Spicy dishes, spices, smoked meats.
• Exotic dishes, citrus fruits.
• Eggs and poultry meat.
• Alcohol, coffee, carbonated drinks.

Let's celebrate! You should definitely “switch” to a hypoallergenic diet and wear clothes made from natural materials. This prevents increased sweating.

Properties

The drug is based on the chemical compound imidazole. The main property is the ability to slow down the synthesis of the membrane of pathogenic cells, i.e. prevents the development and reproduction of fungal spores. Other components included:

“Clotrimazole” against lichen leads to the destruction of the walls between infected cells, a change in the composition of the cytoplasm, which contributes to the destruction of the cellular base. “Clotrimazole” helps get rid of any type of lichen, but most effectively eliminates fungal spores in the pityriasis type of the disease. After taking or applying the drug, it creates a membrane around the fungus - this way it disrupts and prevents the formation of the substance ergosterol. The bacterium stops feeding on healthy cells and microorganisms, and it dies. Additionally, peroxidase activity decreases.

How to treat lichen planus?

Therapy for lichen planus is selected by the attending physician, based on the degree of localization and the individual characteristics of each person.

Ointments such as Flucinar, Dexamethasone, and other drugs are prescribed; Dimexide is chosen for better healing. Areas of skin damaged by lichen planus must be treated with antiseptic drugs.

Antihistamines

Antihistamine medications are prescribed to relieve itching and swelling. After use, many patients note epithelization and slight growth of new cells.

With the development of lichen ruber, antihistamines are prescribed if the disease is the result of contact with an allergen:

• "Tavegil".
• "Suprastin".
• "Erius".
• "Diphenhydramine."

The course of therapy must be carried out for at least 8-10 days; it is recommended to drink it before bed; the drugs have a mild sedative effect.

Medicines should be prescribed by a doctor; if they do not give the desired effect, when lichen planus is observed, hormonal therapy is prescribed.

Let's celebrate! If there is dysfunction in the functioning of internal organs, antihistamines are not prescribed, and it is also not advisable to take them together with immunomodulatory drugs. Otherwise, an allergic reaction may occur.

Sedatives

Sedative medications are prescribed only in cases of urgent need, when the patient has been tense for a long time. Among the most popular drugs are Medazepam and Phenazepam; the course of treatment lasts approximately 10-14 days.

Antibiotics

If lichen planus becomes severe, antibiotics such as:

• "Methacycline."
• "Tetracycline".
• "Doxycycline."

To remove lichen planus, a course of antibiotics is prescribed in tablets or Ceftriaxone, 3 g of Amoxicillin.

Good to know! Drugs such as Erythromycin and Sumamed can reduce swelling and reduce the inflammatory process.

Corticosteroids

Highly effective corticosteroid drugs, such as Clobetasol, Triamcinolone, used 2-3 times a day for 2 weeks. The drug "Clobetasol" can be purchased for 400 rubles, "Triamcinolone" costs 250-350 rubles.

Vitamin complex

To maintain immunity and effectively combat the causative agent of lichen planus in the body, the patient is prescribed injections of nicotinic acid, as well as:

• Retinol.
• Tocopherol.
• Vitamin "B".
• Vitamins "C" and "D".

Let's celebrate! For moderate severity of lichen ruber, vitamin elements are prescribed in the form of tablets, for example, the complex drug “Neovir”. It helps reduce vascular permeability and improve protein synthesis in tissues.

Recommendations

When applying the ointment to the face, you must prevent the drug from getting into the eyes and the skin around them. Monitor changes in your body yourself. If after 3 weeks of treatment there is no positive progress, you should consult a doctor. He will review the established diagnosis and may change the treatment regimen. Other recommendations:

• If an allergic reaction occurs, stop applying the cream or taking the tablets. Visit a dermatologist to relieve discomfort.
• Check the liver during and after completion of treatment, especially for those who have liver disease or even minor problems with it.
• Do not apply bandages to the affected area after applying the ointment, and do not wet or wipe off the cream yourself. You need to wait until it is completely absorbed into the skin.

Be sure to carry out wet cleaning in the house at least once every 2-3 days. Wash things as often as possible.

Wear cotton underwear, which should be changed every day. Synthetic materials will cause skin irritation. This is especially true for those who are treating fungus or lichen in the vagina.

Cleaning the house is an excellent prevention of deprivation