Composition, release form
Zalain is produced in the form of cream and suppositories.
The active ingredient of the drug is sertaconazole. This is a synthetic derivative resulting from the combination of two antifungal components - imidazole and benzothiophene. Thanks to them, Zalain has pronounced activity against mycosis pathogens.
The cream contains:
- sertaconazole 20 mg;
- ethylene glycol;
- palmitostearate;
- paraffin;
- sorbic acid;
- water.
Suppositories are based on:
- sertaconazole 300 mg;
- suppositir;
- vitepsol;
- silicon.
Composition and properties of the drug Zalain
The main form of release of the medicine Zalain is cream and suppositories. This form of release of the drug, as a cream, contains:
- ethylene glycol;
- sertaconazole;
- palmitostearate;
- paraffin;
- sorbic acid;
- water.
The components of the suppositories are silicon, vitepsol, suppotsir and sertaconazole.
Zanail has a pronounced fungicidal and fungistatic effect against pathogens that provoke onychomycosis. In addition, the medication allows you to achieve an antimicrobial effect by destroying gram-positive microflora.
When using the product, the production of ergosterol in the body is inhibited and the permeability of fungal cells is reduced. As a result, the cells become saturated with oxygen and soon die.
Indications
The cream is used to combat fungal infections, the pathogens of which are sensitive to the active component of Zalain in the following diseases:
- dermatomycosis of the skin;
- athlete's foot;
- trichophytosis;
- pityriasis versicolor.
Zalain suppositories are used for local treatment of infections localized on the vaginal mucosa, the pathogens of which are sensitive to sertaconazole, including thrush.
Indications and contraindications
The cream is indicated for use in case of the following diseases:
- epidermophytosis on the legs with involvement of the feet and legs in the pathological process;
- inguinal dermatophytosis;
- fungal infection of smooth skin and hands;
- pityriasis versicolor;
- trichophytosis of the facial skin;
- candidal balanitis and balanoposthitis in men.
Suppositories are used in the treatment of fungal infections of the vagina in women. The use of Zalain is advisable in cases where the pathogen that provoked the onset of the disease is sensitive to sertaconazole.
The instructions for use warn of only one limitation to the use of the drug. This is an individual allergic reaction to the main active ingredient or auxiliary components.
There are no side effects after using Zalain. And only if an allergic reaction occurs, especially if the drug was used for the first time, side effects may occur. This is a rash in the area where the ointment is applied, skin hyperemia, burning and itching.
Before using Zalain for thrush in women and men, you should carefully read the instructions for the drug, which indicate that the permissible norm is one suppository per day during the acute form of the disease. In case of chronic candidiasis, it is allowed to administer a suppository 2 times a day, but only the attending physician should prescribe the duration of the course and dosage of the drug.
The main indications for the use of Zalain suppositories are:
- mixed type infections developing in the vagina;
- vaginal thrush;
- infectious diseases of the vaginal mucosa.
Like any other medicine, Zalain has contraindications and side effects. First of all, it is not recommended to use suppositories if you are individually intolerant to the components of the drug. It is worth knowing that patients who are allergic to imidazole, on which sertaconazole is based, are at risk.
Instructions for use
The duration of treatment with Zalain directly depends on the diagnosis, the severity of the pathological process and the type of pathogen. Therapeutic treatment is recommended to begin with the first symptoms of the disease and continue for at least 14 days after the signs of fungal infection disappear, to eliminate the risk of relapse of the pathology.
Cream. Zalain is applied in a thin layer to the foci of onychomycosis 2 times a day. When processing, it is necessary to capture up to 1 cm of healthy skin areas. In most cases, the symptoms of the disease disappear within 2-4 weeks after starting treatment. The average duration of use of the cream is 1 month.
Suppositories. Zalain is administered into the vagina once a day. The recommended course of treatment is 10-14 days. If after this period the clinical manifestations of the pathology persist, you can repeat the regimen in a week.
Composition and pharmacological action
The antimycotic drug Zalain is available in two dosage forms - suppositories and cream. The main active substance is sertaconazole, which has fungistatic and fungicidal effects. The effect that the medicine has directly depends on the type of fungus that provoked the development of the disease and its characteristics (resistance to medications).
A positive result from the use of the drug is achieved due to its properties to create unfavorable conditions for the growth and reproduction of mycoses. The drug is able to inhibit the synthesis of ergosterol, which provokes a violation of the integrity of the cell membrane of fungi and bacteria, as a result of which they die.
Zalain is used not only for thrush, but also for the treatment of certain types of bacterial colpitis and other pathologies caused by staphylococcus and streptococcus.
Suppositories and cream are intended exclusively for topical use. The medicine exerts its effect on the surface, penetrating only into the nearby layers of the skin and mucous membrane. Destroys the causative agent of the disease and does not enter the systemic bloodstream.
Use in children, pregnant and lactating women
The annotation for Zalain cream does not contain data on its use in pediatric practice. This means that it is not advisable to prescribe the medication to children due to the unknown risk of side effects.
Safety studies have not been conducted in pregnant women. The use of Zalain is possible with the permission of the attending physician. According to numerous reviews, treatment of nail fungus and skin mycoses did not affect the process of gestation and future births.
During lactation, the use of the cream is theoretically possible, since the drug has low absorption and is practically not absorbed into the general bloodstream, so the likelihood of its components entering breast milk is reduced to a minimum. But before using the medication, you should consult a specialist.
ZALAIN (cream)
ova.
I purchased it from the pharmacy chain St. Petersburg Pharmacies, the cost of the ointment is 540 rubles per 20 gram tube. The ointment is packaged in a cardboard box with the name of the product and the manufacturer’s logo.
On the back of the box, the manufacturer described the composition of the ointment and recommendations for the period of use and storage of the cream. Below the manufacturer has provided all its contact information
On the side of the package there is information about the use of the ointment, and the manufacturer also indicated that the ointment is sold only in pharmacy chains and without a prescription.
The ointment is for external use only.
The ointment tube is made of soft aluminum. The name of the product and the manufacturer's logo are printed on the front surface of the cream tube.
On the back of the tube there is information about storing the product and the full name of the manufacturer. The tube has a white plastic screw cap.
The dispenser is not large. The cream is dosed by pressing on the tube, the cream consumption is economical. The cream itself is white in color with a very light, not dense consistency, not greasy, but more watery in structure. Smells like pharmaceutical medicine.
Inside the box was an insert with detailed information about the cream, its use and dosage. I used the cream on the wound twice a day, morning and evening. Before applying the cream, the wound was treated with hydrogen peroxide. At the hospital I was tested for fungus. Although I did not visit any public baths or swimming pools where it is possible to catch such a sore and did not use someone else’s shoes. The only thing was that my feet got wet several times and I had to stay in wet shoes for several hours. It’s only been two days since I used this miracle ointment, the wound on my leg instantly began to heal and almost healed. Tests showed that there was no fungus, which I’m not happy about. And the wound on the leg most likely appeared as a result of prolonged exposure to wet shoes. The ointment turned out to be very effective as a healing agent. I read reviews about it on the site, it is also used for women’s diseases and the effect is quick and positive, it also treats skin diseases. In a word, the ointment really has a productive and operative effect in treatment. I recommend purchasing Zalain cream from the pharmaceutical plant EGIS, but be sure to consult your doctor before using it. I rate the cream excellent for its versatility and quick effect in treatment. Thank you all for your attention to my review!) Be healthy! See you again!)
Additional recommendations
- The drug does not affect the quality of psychomotor reactions, therefore, during treatment with it, restrictions on driving vehicles and working with dangerous mechanisms do not apply.
- The cream should not come into contact with the mucous membrane of the eyes. In case of emergency, it is recommended to rinse them with sufficient water.
- If fingernail or toenail fungus is caused by candidiasis, you should not use highly acidic detergents to treat them. They neutralize the effect of Zalain and contribute to the spread of infection.
- Areas of the nail and skin affected by mycoses must be kept dry to ensure proper tissue care and speed recovery.
- The product is well tolerated when treating damaged areas of onychomycosis; the drug does not cause irritation or burning.
Side effects
According to the instructions, undesirable reactions to Zalain cream include contact dermatitis, peeling and hyperpigmentation of the skin.
If such conditions develop, it is recommended to discontinue further use of the medication. The symptoms that arise will go away on their own in the near future without any consequences.
Analogs
Zalain has no structural substitutes. But on the shelves of pharmacies you can find a sufficient range of medicines that have the same active ingredient or its synthetic derivatives. Let's look at them in the table.
Drugs | Description |
DERMAZOL | Available in the form of tablets, cream, shampoo and suppositories. The basis of the medication is ketoconazole, an imidazole derivative. It is prescribed in the fight against various fungal infections due to its convenient release form and wide spectrum of action. The price of Dermazol cream is 225 rubles in Russia and 39 hryvnia in Ukraine. |
MYCOSPOR | Another drug based on an imidazole derivative, like Zalain. Its active ingredient is bifinazole and additionally contains urea, which improves the therapeutic effect of the drug. The medicine has a wide range of effects, destroying almost all known pathogens of mycosis. Mikospor cream costs 520 rubles in Russia and 190 hryvnia in Ukraine. |
CLOTRIMAZOLE | An affordable and effective drug based on the component of the same name - clotrimazole . It is used not only in the fight against nail and skin fungus, but is also active against protozoa and bacteria. The cost of the drug in Russia starts from 27 rubles, in Ukraine - from 12 hryvnia. |
Whether it is necessary to replace Zalain and which drug to choose to treat the fungus should be decided by the doctor based on the diagnostic examination performed and the patient’s health characteristics.
Where to buy, price and analogues of the product
You can purchase the drug in cream form at any pharmacy. In Russia, the cost of a 20 ml tube is 450-470 rubles, depending on the region of sale.
To date, there are no structural substitutes for Zalain cream in pharmacies. At the same time, you can purchase medicines that have one active ingredient or its synthetic derivatives. The following drugs are analogues of Zalain cream:
- Dermazol;
- Clotrimazole;
- Mikospor.
When treating onychomycosis, it is recommended to check with your doctor whether Zalain can be replaced with any analogue. Usually the decision is made based on the results of a diagnostic examination and a study of the characteristics of the patient’s health condition.