Composition and release form
The basis of the drug Azelik is azelic acid, which helps cleanse the ducts of the sebaceous glands, fights the appearance of acne, reduces the formation of comedones, and reduces the number of bacteria (staphylococcus, propionic bacteria) on the surface of the skin. The dose of acid per 100 g is 15 g.
The gel contains excipients: benzoic acid, squalane, methylpyrrolidone, macrogol cetostearate, dimethicone propylene glycol, disodium edetate, sodium hydroxide, carbomer interpolymer, purified water. The active elements of all compounds interact with each other, enhancing the therapeutic effect of the drug.
Azelik is produced by a Russian manufacturer in gel form. It has a white or almost white color with a faint odor.
Packaged in tubes with a 5g, 15g or 30g dispenser. Packed in cardboard boxes with detailed instructions inside.
Azelik analogues and prices
Dosage form : gel for external use Composition 100 g of gel contains: active substance: azelaic acid in terms of 100% substance - 15 g; excipients: benzoic acid 0.1 g, methylpyrrolidone 4 g, squalane 1 g, propylene glycol 8 g, disodium edetate 0.1 g, sodium hydroxide 0.25 g, dimethicone 1 g, macrogol cetostearate 1.4 g, carbomer interpolymer 1 .4 g, purified water up to 100 g. Description White or almost white gel, a slight specific odor is allowed. Pharmacotherapeutic group : acne rash treatment ATC code : D10AX03
Pharmacological properties: Pharmacodynamics It has bacteriostatic activity against Propionibacterium acne and Staphylococcus epidermidis, reduces the production of fatty acids that contribute to acne. Reduces the formation of comedones. By influencing the process of keratinization of epidermal cells, it suppresses the growth and activity of abnormal melanocytes that cause hyperpigmentation such as melasma. Has an anti-acne, depigmenting effect. Pharmacokinetics: After application to the skin, it penetrates the epidermis and dermis, 3.6% of the total dose is absorbed into the systemic circulation. Part of the absorbed acid is excreted by the kidneys unchanged, part - in the form of dicarboxylic acids (C7, C5), formed as a result of beta-oxidation. Indications for use: Acne vulgaris, rosacea. Contraindications Hypersensitivity to the components of the drug. With caution Pregnancy, lactation period. Use during pregnancy and breastfeeding During pregnancy and breastfeeding, use only if the expected benefit to the mother outweighs the risk to the fetus and child. Directions for use and dosage : Externally. The gel should be applied to previously thoroughly washed (with water or cleansed with a mild cleansing cosmetic) and dried facial skin. The gel is applied in a thin layer to the affected areas of the skin 2 times a day (morning and evening) and lightly rubbed in. Approximately 2.5 cm of gel is enough for the entire face. In patients with acne vulgaris, significant improvement is usually observed after 4 weeks. To obtain the best results, use of the drug should be continued for several months. Side effects At the beginning of treatment, local irritation, hyperemia and peeling of the skin, burning, erythema, itching are possible, which usually cease during treatment. Allergic skin reactions are possible.
Overdose Currently, no cases of drug overdose have been described. Interaction with other drugs Can be used in combination with other drugs for the treatment of acne. Special instructions Avoid contact of the drug with the eyes, as well as the mucous membranes of the nose, lips and mouth; in case of accidental contact, rinse immediately with water. In cases of severe skin irritation in the first weeks of treatment, the gel can be used once a day; Short-term withdrawal of the drug is also possible. After the symptoms of skin irritation disappear, regular use of the drug at the recommended dose should be resumed. During treatment, it is necessary to protect the skin from the entire spectrum of solar radiation. Release form Gel for external use 15%. 5 or 30 g in an aluminum tube. Each tube, along with instructions for use, comes in a cardboard box. Storage conditions : At a temperature not exceeding 25 °C. Do not freeze. Keep out of the reach of children. Shelf life: 2 years. Do not use after the expiration date. Conditions for dispensing from pharmacies Without a prescription. Manufacturer. Claims are accepted at the address: Open Joint-Stock Company "Chemical and Pharmaceutical Plant "AKRIKHIN" (JSC "AKRIKHIN"),
Azelik's action
Thanks to its texture, the drug is easily applied to the skin, quickly absorbed without clogging the pores. Penetrating deep into the epidermis, the gel begins its therapeutic effect. Azelik has a broad effect:
- eliminates harmful bacteria in the layers of the epidermis;
- normalizes the process of exfoliation and keratinization of the skin;
- has an antioxidant effect;
- reduces the inflammatory process of the skin;
- eliminates redness from rosacea;
- has a depigmenting, anti-acne effect;
- reduces the amount of sebum;
- cleanses pores.
Azelik has a bactericidal effect, which prevents the formation of acne vulgaris and is an excellent product for caring for problem skin. This gel is not addictive and does not affect the functioning of the liver or kidneys.
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Indications for use of Azelica
The medicine is used in the treatment of inflammatory skin diseases and is prescribed in the following cases, providing a positive therapeutic effect:
- rosacea at all stages;
- acne;
- acne comedonica, acne vulgaris;
- oily skin;
- the presence of harmful bacteria - propionibacteria, epidermal staphylococcus;
- sebaceous plugs;
- ulcers;
- pigmentation after inflammation;
- black dots.
The influence of Azelik in the last stages of the inflammatory process, when free fluid is formed in the foci, helps prevent the appearance of purulent lesions that affect the occurrence of re-infection.
Contraindications and side effects
The drug Azelik has a minimum number of contraindications and is one of the safest medications; it is used in complex treatment with anti-inflammatory drugs in the treatment of acne. The gel should not be applied if you have an individual intolerance to the components that make up the medicine. It is not recommended to take the product in summer, as ultraviolet radiation can cause age spots and numerous freckles. During pregnancy and breastfeeding, the drug is used only after consultation with your doctor.
Side effects from the use of Azelik occur in small cases and manifest themselves in the form of a feeling of skin tightness, itching, burning, peeling at the site of use of the ointment. Rarely: blisters, rash, urticaria.
Symptoms disappear on their own when the drug is discontinued. If undesirable consequences persist for a long time, you should consult a specialist.
Acne treatment
Acne is a disease caused by many factors. A significant role in its occurrence is played by genetic predisposition, hormonal disorders, improper care and unbalanced nutrition. In order to get rid of acne, it is important to find out the cause of their appearance and only then begin treatment.
Common to the treatment of all types of acne is proper skin care and the use of products with azelaic acid - Skinoren or Azelica.
Azelaic acid, which is part of these creams, has a keratolytic, antimicrobial and anti-inflammatory effect.
The principle of its operation:
- The product penetrates into keratinocyte cells, disrupts the structure of their DNA, slows down growth and division, thereby preventing excessive keratinization of the skin.
- Excessive keratinization leads to blockage of the gland duct, accumulation and oxidation of sebum, and hence to the formation of acne and blackheads. By reducing the thickness of the stratum corneum, the function of the sebaceous glands is normalized, and the skin remains clean.
- Azelaic acid molecules, in addition to epidermal cells, also enter the cells of pathogenic microorganisms - bacteria and fungi, leading to their death, which means they have antimicrobial properties.
Skinoren and Azelik are the most commonly prescribed effective acne creams by dermatologists. Despite the almost identical composition, there are differences between these two drugs, and a specialist should choose the drug suitable for treatment after a thorough examination.
Instructions for use
The gel is applied to previously cleansed skin with a mild cosmetic or water and then dried. A strip of medication 2 - 2.5 cm long is applied in an even layer to the affected areas of the skin until completely absorbed with light massaging circular movements. The amount of gel spent depends on the area of the lesion. Apply 2 times a day - morning and evening, with an interval of 10 - 12 hours. Depending on the stage of the disease, the duration of the course is from four to five months.
The minimum course completion is at least four weeks.
For progressive disease, Azelik is prescribed as part of complex therapy. A relapse may occur in the first week of using the product. In such cases, it is necessary to reduce the amount of use of the drug to once a day. After inflammation disappears, the dose should be increased to twice a day.
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What is the difference between Azelik and Skinoren?
Azelik or skinoren, which is better? – a question that interests many patients faced with acne. Treating acne is a lengthy process, which can be very expensive when using only brand-name products. Generics have a composition similar to the original drug, but are cheaper, so they are used to reduce the cost of treatment.
Azelik is a gel for external use containing 0.15 g of azelaic acid per 1 g. Products. Unlike Skinoren, it is not available in a dosage of 20%. Excipients are similar to Skinoren; methylpyrrolidone and squalane are additionally used.
The treatment regimen is similar to the original drug - it should be applied twice a day to previously cleansed and thoroughly dried skin. The duration of therapy is determined by the doctor; for acne vulgaris it averages 3-4 weeks.
Additional Information
Before you start using Azelik, you need to make sure that there is no allergic reaction to this gel. To do this, squeeze out a small amount of the drug and then rub it on the wrist, wait 20 minutes. If there are no allergy symptoms, the medicine is ready for use.
For the treatment of rosacea, the gel is approved only for people over 18 years of age. When eliminating acne, the drug is recommended for children over 12 years of age. Azelik is prescribed only if systematic skin rashes occur or the affected surface area is large. If you have dry skin, the use of Azelic is not recommended.
Apply the product to the skin with caution, avoiding accidental contact with the eyes or mucous membranes of the nose and mouth. In case of contact, quickly rinse the affected area with running water. During course therapy, it is advisable to stop drinking alcohol, since alcohol changes the pharmacological properties of the gel, aggravating the course of the disease.
Store the medicine out of the reach of children in a specially designated place, at a temperature of no more than 25 degrees. Avoid ultraviolet rays; discard the gel after the expiration date. The shelf life is two years from the date of manufacture.
Azelik is sold in pharmacies without a doctor's prescription and is freely available. The cost of this product depends on the volume and on average is: 5 grams - from 300 rubles, 15 grams - from 450 rubles, 30 grams - from 650 rubles. The price may vary depending on the region of residence and the pharmacy chain.
What to choose, Azelik or Azix Derm?
Hello!
The main and only active ingredient in these preparations is azelaic acid. And what is really important to pay attention to here is the concentration of the active substance.
Let's take a point-by-point look at what you were told.
Aurora wrote:
Less price, almost 200 rubles (570 versus 740); Azix has a higher concentration of azelaic acid (and this, in his words, means that it will be more effective); It does not cause such irritation as azelik; Same volume;
- It is very strange that the price of Azix-derm cream is so much lower. Since it is produced abroad, namely in India, it means that it is bought with foreign currency. I admit that the price is lower due to the large volume of production and a more technologically advanced enterprise than in Russia (Azelik is produced in the Moscow region). Well, or the pharmacy is simply getting rid of stale remains.
- Yes, the concentration is indeed 5% higher, and the desired effect will be expressed and achieved faster. However, please note that azelaic acid may cause irritation. And the thinner and more sensitive the skin, the stronger the reaction to the active substance can be. (you can read reviews of Azelik in this thread: https://pro-lico.ru/forums/topic/azelik-i-klindovit-dlya-lecheniya-akne)
- I repeat, in any preparation that contains azelaic acid, the skin reaction can be the same as I described above. And it is very strange that a specialist says such things, because the lower the concentration of the active substance, the less likely side effects are to occur - this is an axiom. And most likely, your drug prescribed Azelik precisely because of the reduced concentration, and not because of collusion with the pharmaceutical company or pharmacy.
- The same volume at a lower price is really a plus
To summarize, I can give you this recommendation. If you have thin, sensitive, dry and irritation-prone skin, then you should definitely buy Azelik, since it has a lower concentration and is less likely to cause side effects. It’s even better to buy it in a volume of 5 grams, the cost will be half as much, which is not particularly profitable when calculating price-volume, but this way you can understand exactly how your skin will react. If everything goes well, then you can buy Azix-derm.
However, if your skin is fine and is not prone to irritation, then you can immediately purchase Azix and start treating rashes. If you have any other questions, be sure to contact us!
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2012-2017 Graduated from the Federal State Budgetary Educational Institution of Higher Education of the State Medical University of the Ministry of Health of Russia in Smolensk with a degree in Pharmacy.
Azelik's analogs
There are a significant number of analogues of Azelik gel that have the same therapeutic properties and are similar in their mechanism. These include:
- Skinclear.
- Doxycycline.
- Skinoren.
- Baziron AS.
- Metrogyl - gel.
- Ugrin.
- Isotrekin.
- Azix - Derm.
- Differin cream.
In some cases, when side symptoms appear, the doctor selects a replacement for this drug, which is similar in its composition and similar in its effect.
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