Differin or Baziron – which is better in combination, differences, reviews

Acne and pimples are the main manifestation of problem skin. They cause a lot of inconvenience to their owners. Hateful rashes are not aesthetically pleasing, and a person covered with acne invariably begins to feel complex, shy around others and limit himself in communication. Recently, dermatologists are increasingly prescribing to their patients imported gels and creams Differin and Baziron, which are recognized as highly effective in the fight against acne and acne. Let's figure out what explains their good effect and how these remedies differ.

What is Differin

Differin is a drug produced by the famous French pharmaceutical concern Galderma. The main task of this medication is to eliminate facial skin defects.

Release form

The drug has been on the market for several years and has already proven itself to be positive. The main active component of Differin is adapalene (a synthetic analogue of a retinoid). The product is presented on the market in the form of:

• Gelya.
• Crema.

It is recommended to purchase the gel for people with normal and oily skin types, and the cream for patients with dry skin.

Operating principle

Differin mainly affects epithelial cells located inside and outside the hair follicle. It is known that acne appears due to the active secretion of sebum, which leads to clogging of pores. Additionally, dead cells of the stratum corneum, which periodically exfoliate, contribute to blockage.

The synthetic retinoid included in the composition reduces and normalizes the processes of keratinization in the lumen of the follicle. Due to this, the substance not only prevents the formation of new acne, but also helps eliminate old ones.

Side effects and contraindications

Differin as such has no contraindications and is recommended for use in patients over 9 years of age. The only exception may be people who cannot tolerate the components included in the drug. An additional side effect is severe peeling in certain areas of the skin. However, this phenomenon is observed only in the case of frequent use of the cream or gel.

Differin is a potent medication, and therefore it is recommended to use it once a day in the morning or evening after washing your face. In addition, the gel should be applied exclusively to the affected areas.

IMPORTANT! It is worth noting that Differin is only effective against acne. Ointment does not help against acne.

How does Zinerit work?

Erythromycin is an antibiotic that fights a huge number of microorganisms that can cause acne. Zinc reduces the production of skin secretions and has an anti-inflammatory, astringent, and antiseptic effect. Both substances work by providing a synergistic effect, that is, they enhance each other.

It is necessary to prepare a two-component solution, which is applied to the skin with an applicator. Before each use, prepare a new solution.

• Apply to cleansed skin twice a day: in the morning and before bed, no need to rinse off. You can apply makeup over the drug.
• A noticeable effect is visible after 2 weeks, the course of treatment lasts 1.5-2 months (caution: long-term use of antibiotics!).
• "Zinerit" contains an alcohol component and can dry out the skin.

Prices, dosage, consumption of the drug

“Zinerit” is available in powder form, accompanied by a colorless solvent for preparing the solution. The volume of medicinal lotion is 30 ml.

The price for “Zinerit” varies from 500 to 900 rubles per package.

The manufacturer calculates the consumption of the product for 5 weeks, but for extensive lesions the drug is enough for 3 weeks.

What is Baziron AC

Baziron AC is also developed by the French pharmaceutical company Galderma. The drug is also intended to combat skin defects, however, it has a different composition.

Release form

The main active ingredient of Baziron is benzene peroxide, due to which the product has a quick effect. Available in the form of a gel with the following percentage of active ingredient:

• 2.5% - for sensitive skin.
• 5% - for normal skin.
• 10% - for oily skin.

The gel is great for both children over 12 years old and adults.

Operating principle of Baziron

It is known that due to the active secretion of sebum and dead skin cells, a kind of plug is formed on the epidermis, which clogs the excretory canal. A clogged pore is a breeding ground for microorganisms that cause inflammatory processes or, more simply, the appearance of pimples and ulcers.

Thanks to benzene peroxide and other components, Baziron has an antibacterial and anti-inflammatory effect. Accordingly, the gel applied to the affected area destroys harmful microorganisms, while simultaneously relieving inflammation. Thanks to this, after just a few hours, pustules and pimples are significantly reduced in size.

IMPORTANT! Baziron AC is not a drug belonging to the group of antibiotics. However, it can remove up to 90% of pustules and pimples in just seven days.

In addition, Baziron is considered a more effective medication than its analogues, which are based on antibiotics. And there is a simple explanation for this. The fact is that bacteria that cause acne over time acquire resistance, causing antibiotics to become ineffective. Benzene peroxide is not addictive to bacteria, and therefore it perfectly eliminates dermatological facial defects.

Side effects and contraindications

The only drawback of Baziron is that it dries out the skin a little, causing flaking. Therefore, you should definitely use a moisturizer after using it. In addition, it is contraindicated for a certain list of persons. Namely:

• Children under 12 years old.
• Pregnant women.
• Mothers who are breastfeeding their babies.
• Persons who cannot tolerate the individual components contained in Baziron AC.

Additionally, the course of treatment with this drug should not exceed 3 months.

Comparative characteristics of drugs

Baziron
Dermatological agent with strong antimicrobial and antiseptic effects. The main indication is the treatment of acne.

The active component of the drug is benzoyl peroxide, a substance that suppresses the proliferation of pathogens that promote inflammatory processes in the dermis. In addition, benzoyl anhydrous has a keratolytic effect, improves oxygen saturation of tissues, and normalizes sebum secretion.

The drug is quite safe for the body, since the absorption of the medicinal substance is very low. A small part of the drug is absorbed through the skin. Basically, after applying the drug to the surface of the dermis, benzoyl is quickly transformed into benzoic acid, which then passes into the circulatory system and is excreted at a high rate by the kidneys. Therefore, the drug does not linger in the tissues and does not have a negative effect on health.

Baziron is produced in the form of a gel, which is available with different concentrations of the active substance: 25, 50 and 100 mg per 1 g of drug.

Differin

The medication is intended to eliminate acne, but its therapeutic effect is carried out with the help of adapalene. The substance is an artificially synthesized analogue of retinoic acid.

The mechanism for eliminating acne has not yet been fully studied, but it is believed that adapalene normalizes the condition of epithelial cells, promotes keratinization, and blocks the occurrence of microcomedones.

The substance has anti-inflammatory properties and is well tolerated, as it almost does not irritate the dermis. The therapeutic effect appears 1-2 weeks after the start of therapy, and a lasting result is observed 2-3 months after the first procedure.

Differin or Baziron

Of course, Baziron and Differin are effective drugs that eliminate acne on the face. However, to answer the question, what to choose? It is necessary to look at the main differences between ointments. Namely:

• Release form. Differin is available in two forms, while Baziron is in gel form. Accordingly, the first drug has an advantage in terms of ease of application.
• Therapeutic effect. Unlike Differin, Baziron quickly eliminates the rash, making it a kind of “lifesaver” for people. On the other hand, the end result of both drugs is almost the same.
• Contraindications. Baziron's composition is more aggressive relative to its opponent. Based on this, it is not indicated for use by everyone.

That each product has its own advantages and disadvantages, and therefore even dermatologists have difficulty saying, when faced with the question “which is better?”

Online magazine about choosing the best goods and services

31.07.2019 17:40:39

Expert: Boris Kaganovich

Differin and Baziron AS are drugs for the treatment of acne. They have different compositions, so you can see differences in contraindications and features of use. We studied the features of these drugs to understand which one is better.

Differin is available in two dosage forms - cream and gel. This is a drug for the treatment of acne. It has keratolytic, anti-inflammatory, comedolytic, sebostatic effects. The active ingredient is adapalene. Manufacturer: Laboratoires Galderma in France. Available in pharmacies without a prescription.

Adapalene is a retinoid metabolite with anti-inflammatory and comedolytic properties. The action of the substance is based on interaction with receptors of epidermal cells. Under the influence of adapalene, the prerequisites for the appearance of microcomedones are reduced. The substance acts on inflammatory factors by metabolizing arachidonic acid and inhibiting leukocytes.

Absorption of the local product is very low - up to 5%. It is excreted from the body with bile.

Research and effectiveness

Differin is a highly effective basic treatment for acne. To obtain the desired effect, it is recommended to use it for 4-6 months.

Randomized studies show that Differin reduces the number of inflammatory and non-inflammatory elements of the rash. For lasting results, maintenance therapy is required for 3 months.

The effectiveness of the drug largely depends on the particle size of the active substance. In Differin, this figure is 3-10 μm, which ensures delivery of the product to the sebaceous hair follicle. Distribution of adapalene occurs within 5 minutes after application.

Sources:

1. External acne therapy: medical choice. Pharmateka. Belousova T.A. 2012.
2. Read more about the drug Differin cream. Medi.ru. Details about medications. From March 1, 2012.

Contraindications

A strict contraindication to the use of cream and gel would be hypersensitivity to the composition, namely an allergy to retinoids, retinoic acid analogues and auxiliary components in the composition of the product.

It is not recommended to combine Differin with cosmetics that dry out the skin. Relative contraindications that require consultation with a doctor include skin tumors, eczema, seborrheic dermatitis, and burns. For children, during pregnancy and lactation, it is also not recommended.

Side effects

The gel and cream are well tolerated. Of the rare side effects, the most likely will be skin irritation, especially when exposed to sunlight.

Very rare unwanted symptoms include:

1. dry skin;
2. peeling;
3. burning;
4. itching;
5. hypo- and hyperpigmentation;
6. worsening of the rash;
7. allergic conjunctivitis;
8. increased likelihood of sunburn;
9. contact dermatitis.

Dosage

The product can be applied to the entire face and spot-on, directly on acne. For mild acne, using only this drug is sufficient. For severe acne, Differin is used in combination with other agents.

Before use, you need to wash your face. Differin is applied 1-2 times a day, without rubbing into the skin. The course of treatment is from 3 months. The maximum effect is observed from the first month of use. The gel is best used for oily skin types, but not for dry skin types.

Low absorption of the drug almost completely eliminates the possibility of overdose. With prolonged uncontrolled use, increased adverse reactions may occur. An overdose in this case may resemble hypervitaminosis A. A doctor's help is needed.

Who is it suitable for?

Differin is used for mild, moderate and severe acne. Can be used as a single drug and in combination with other drugs, such as antibiotics, antiandrogens.

Description of Baziron AS

Baziron AS is an anti-acne drug with a disinfectant and antimicrobial effect. It contains benzoyl peroxide. Available in gel form. Manufacturer: Galderma.

Cost and analogues

Which drug is better

Differin and Baziron AS are effective in the treatment of acne. For oily skin types, it is better to choose the second option. This is due to the fact that Baziron AS normalizes the functioning of the sebaceous glands. For persistent inflamed acne on the face, it is better to use Differin, because in just one night it can significantly reduce the severity of the inflammatory process.

Baziron AC is recommended for use in the morning and evening, and Differin can be applied only once a day. For acne in adolescence, only Baziron is suitable, since the second drug is contraindicated under 18 years of age.

Consumer Opinion

Maria, 25 years old: acne appeared after pregnancy, the reason turned out to be a decrease in immunity and postpartum stress, in combination with vitamins, a sedative, Zinerit proved to be effective.

Elena, 16 years old: teenage acne on her face appeared late. Daily one-time spot application of Zenerite eliminated the problem.

Anna, 14 years old: I tried both remedies. When there was a lot of acne, I purchased Bazeron 10%. After it, I use Zenerit for prevention. The dermatologist explained that Baziron is a medicinal ointment, and Zinerit is an antiseptic. Both creams were effective. But you shouldn't use them together.

Andrey, 15 years old: Acne flares up in autumn and spring. I use Baziron during these periods. In summer and winter I get rid of single pimples with the help of Zinerit.

Zhenya, 18 years old: Disturbances in the functioning of the endocrine system affected the face in the form of rashes and white pimples. The dermatologist recommended Bazeron. Its effect began to appear only after a week of use. Now I use Zenerit.