How to use Nizoral for seborrheic dermatitis

Composition and release forms

The drug Nizoral in any form of release has high antifungal properties

Nizoral is a fungal remedy available in three dosage forms:

• flat, round tablets with a beveled edge and a scoring line. Available in blisters of 10 capsules, each containing 200 mg of active ingredient;
• cream for topical use, white in color and uniform in structure, available in aluminum tubes of 15 g. Concentration of the active substance - 2% (20 mg);
• The shampoo is red-orange in color and is available in polyethylene bottles of 25 or 60 ml. The concentration of the active substance is 2% (20 mg).

The drug contains a synthetic biologically active substance - ketoconazole, as well as auxiliary components: purified water, dyes, flavors, cellulose, starch, fatty acid derivatives.

How to use for nail fungus

Nizoral is often used against a fungus that has infected the nail plate of the fingers or toes. The cream helps to quickly stop the development of the pathological process if it occurs in a mild form. In the advanced stage, it is best to use tablets that have a stronger effect and act on the pathogen from the inside.

Before applying the topical drug, it is strongly recommended to wash your hands or feet well and then pat them dry with a towel. Particular attention should be paid to the nail area. After this, you can begin processing.

pharmachologic effect

Nizoral has significant antifungal properties, providing both fungistatic and fungicidal effects. The drug disrupts metabolic processes and the production of lipids and ergosterol, which are necessary for the creation of the cell membrane of the fungus. The destruction of the cell membrane prevents pathogens of fungal infections from forming colonies: they stop reproducing and gradually die.

Nizoral is effective against many types of pathogenic fungal organisms:

• yeast fungi;
• dimorphic fungi;
• dermatophytes;
• eumycetes;
• microsporia causing lichen;
• candid;
• cryptococks;
• streptococci;
• staphylococci;
• fungi - causative agents of seborrhea.

Nizoral helps eliminate the symptoms of fungal infection, such as itching, peeling, rashes, alleviating and completely relieving them even before the pathogens are completely destroyed. When taken orally, Nizoral is well absorbed in the gastrointestinal tract. The maximum concentration of the active substance in the blood is reached within two hours and is well excreted by the kidneys and intestines. When used topically, the product does not enter the bloodstream even after prolonged use.

Indications for use

If lichen pathology occurs, doctors prescribe the drug Nizoral

Nizoral in tablet form is prescribed for fungus of the skin, mucous membranes, and scalp. Most often they are prescribed in the absence of a response to local therapy, or if the use of creams and ointments against the fungus is impossible: in the presence of large affected areas, or when the infection has entered the deep layers of the epidermis. The drug is used for the following pathologies:

• versicolor and pityriasis versicolor;
• dermatophytosis;
• fungal folliculitis;
• skin candidiasis;
• candidiasis of the mucous membranes of the mouth and larynx;
• vaginal candidiasis;
• coccidioidosis;
• paracoccidioidosis;
• blastomycosis;
• histoplasmosis.

Nizoral cream or ointment is used to relieve fungal skin diseases caused by certain strains of pathogens:

• pityriasis versicolor;
• athlete's foot inguinal;
• skin candidiasis;
• seborrhea;
• smooth skin dermatosis;
• epidermophytosis of the hands and feet.

Nizoral in the form of shampoo is used as a therapeutic treatment and prevention of dandruff, lichen and seborrhea affecting the scalp, groin area, chest in men.

Shampoos for children against seborrhea

Seborrhea medications are selected individually and after consultation with a doctor. It must be remembered that shampoo for children should be hypoallergenic and mild so as not to dry out the delicate scalp. The most popular means:

The doctor may prescribe Sebiprox for the child.

• "Nizoral";
• "Dermazol";
• "Friderm zinc";
• "Sulsena";
• "Sebiprox";
• Shampoos with salicylic acid.

Treatment of seborrhea in children also includes a set of techniques, including the use of vitamin B, nutritional adjustments and taking antifungal drugs. For babies, oil is added to shampoos to soften the effect. After getting rid of seborrheic dermatitis, you need to treat all things with a vinegar solution and then wash them. It is important to remember that the earlier the symptoms of dermatitis are detected in a child, the greater the chance of quickly coping with the disease.

Instructions for use

You need to use Nizoral against fungus exactly following the instructions for use. It is recommended to begin treatment after undergoing an examination and consultation with a doctor. The specialist will determine exactly what type of pathogen caused the disease and whether the drug will be effective against it. When treating systemic fungal diseases using the drug in tablet form, the doctor will help you choose an individual dosage and duration of therapy.

It is important to undergo a re-examination after completing the course of treatment: this is necessary to make sure that the infectious agent is completely destroyed. If you stop using the product immediately after the symptoms disappear, there is a high probability that the disease will recur.

Shampoo

Nizoral in the form of shampoo is applied to infected hairy areas of the skin for 5 minutes, after which it is thoroughly washed off. To prevent dandruff and seborrhea, it is recommended to use it once every two weeks. To prevent the development of pityriasis versicolor, it is advisable to carry out a course of use of the product before the start of the summer season: you need to use shampoo once every three days for 2-3 weeks.

To get rid of dandruff and seborrhea, fungal-infected areas are treated with Nizoral 2 times a week for a month. For lichen, use shampoo once a day for five days. The product can be used by both adults and children.

Cream

The cream is convenient to use when the skin is affected by fungus

Nizoral in the form of an ointment is applied once a day to the areas affected by the fungal infection, treating the surrounding healthy skin to prevent the spread of the pathogen. The duration of treatment varies depending on the disease, its form and severity:

• yeast infection – 2-3 weeks;
• athlete's foot – 1-1.5 months;
• inguinal athlete's foot – 2-3 weeks;
• pityriasis versicolor – 2-3 weeks;
• dermatomycosis of smooth skin – 1 month.

To eliminate seborrhea, treatment is carried out 1-2 times a day until the negative symptoms are completely eliminated. As a rule, complete cure occurs after 2-4 weeks of use. Nizoral cream helps against nail fungus, but only when less than 40% of the nail plate is affected. Otherwise, in addition to local treatment, you will need to take the drug in tablet form.

The ointment can be used after recovery to prevent relapses by lubricating the affected areas 1-2 times a week. Apply the product in a thin layer

Pills

Nizoral tablets are taken orally with meals. The average dosage is calculated depending on the age and weight of the patient:

1. For adult patients weighing more than 30 kg: 1 capsule once a day, for candidiasis - 2 capsules.
2. Children weighing from 15 to 30 kg – half a tablet once a day.

In the absence of a therapeutic effect, the dosage is increased, but only after consultation with the attending physician.

The duration of treatment depends on the disease and its severity:

• vaginal candidiasis – 7 days;
• versicolor and pityriasis versicolor – 10 days;
• infections of the scalp - 1-2 months;
• candidiasis of the skin and mucous membranes – 2-3 weeks;
• mycosis of the skin caused by dermatophyte fungi – 1 month;
• paracoccidioidomycosis, coccidioidomycosis, histoplasmosis – more than six months.

Treatment continues until the pathogen is completely destroyed, which must be confirmed by undergoing examination at a medical facility. If negative symptoms appear, you should stop taking Nizoral orally and consult a doctor.

Use during pregnancy

Nizoral in tablet form is prescribed during pregnancy only in cases where the possible beneficial effect significantly outweighs the potential risk to the health of the fetus. Ketoconazole is concentrated in the bloodstream, excreted in biological fluids, including breast milk, and easily penetrates the hemoplacental barrier. If the use of the drug during lactation is necessary for medical reasons, breastfeeding is temporarily stopped.

Despite the fact that topical use of Nizoral does not result in the active substance entering the bloodstream, the drug in the form of shampoo and ointment is also not recommended for use during pregnancy. There is currently no exact information about how safe it is to use the product externally during pregnancy and breastfeeding.

The principle of action of the drug

Nizoral shampoo is an effective antifungal agent for external use. He can safely be considered a time-tested expert in the fight against dandruff. Not every drug can boast such a long history in the pharmaceutical market. The drug first became known in 1976, and to this day it manages to remain popular and in demand in the fight against an unpleasant defect.

The drug can not only eliminate cosmetic problems of the scalp, but also eradicate the cause of their occurrence. The product contains ketoconazole. This substance inhibits the growth and promotes the death of harmful microorganisms, fungi, which provoke the development of pityriasis versicolor and seborrheic dermatitis.

The manufacturer recommends using Nizoral shampoo for:

• dandruff;
• seborrheic dermatitis;
• pityriasis versicolor.

In addition to shampoo, the manufacturer offers Nizoral tablets and cream. Many experts claim that the cream guarantees greater effectiveness because it stays in contact with problem areas of the scalp longer. But in tablets the concentration of the active ingredient is the highest - 200 mg per 1 capsule.

Composition and benefits

Nizoral anti-dandruff remedy is a red-orange liquid, thick in consistency, with a specific odor. The main active ingredient is ketoconazole, in a proportion of 20 mg per 1 g of shampoo. Ketoconazole particles penetrate every cell of the harmful fungus, stop its growth and destroy the cell membrane, making them defenseless and weakened.

For deep and high-quality cleansing of the scalp from accumulated dandruff flakes, surfactants (surfactants) are added to the composition. These include coconut oil fatty acid diethanolamide and disodium lauryl sulfate.

To stabilize the acid-base balance and complement the antimicrobial effect of the product, the composition contains hydrochloric acid and imidourea. It is impossible to miss the presence of cosmetic fragrances, flavors and dyes in the preparation.

Important point! Despite the rich synthetic composition, Nizoral shampoo can be used during lactation and pregnancy.

Advantages and disadvantages

Among the advantages and positive qualities of the Nizoral product, experts and users note:

• highly effective in combating fungal diseases of the scalp, confirmed by 64 clinical studies and user reviews;
• affects the problem from the inside, having a detrimental effect on the causative agent of the disease;
• suitable for the treatment and prevention of dandruff in the hair;
• can be used during lactation and pregnancy, for the treatment of children and adolescents;
• has a minimum of contraindications;
• foams well;
• easy to use;
• Sold in a pharmacy, dispensed without a doctor's prescription.

Of the negative qualities, users noted:

• high cost of the drug;
• the composition contains dyes, fragrances, disodium lauryl sulfate and a number of other synthetic additives that can cause side effects and an allergic reaction;
• lack of natural nutritional supplements, oils and plant extracts that would soften the aggressiveness of the chemical composition and active substance;
• can give bleached and gray hair an extraneous tint. To eliminate it, just wash your hair with regular shampoo.

Price

The cost of Nizoral is quite significant. The shampoo is available in volumes of 25, 60 and 120 ml. For the purchase of a small bottle you will pay from 750 rubles.

The product is used sparingly. For example, one package is enough for 1.5–2 months when treating seborrheic dermatitis. If Nizoral is intended for pityriasis versicolor, it is advisable to purchase a large package.

It is strictly prohibited to use a product that has expired.

Contraindications

Individual intolerance to the components of the drug is the main limitation for the use of Nizoral products. Otherwise there are no contraindications.

Before first use, test the composition for allergies. To do this, apply a few drops of the product to sensitive skin. The appearance of a strong burning sensation, redness at the site of contact with the drug is an allergic reaction, this product should not be used.

Risks of use during pregnancy and lactation

As for the treatment of dandruff and skin diseases in women during pregnancy, there is no data on harm caused to the baby in the womb. Given the aggressiveness of ketoconazole, when prescribing the drug, the expected therapeutic effect is compared with possible harm to the health of the fetus.

Contraindications

If individual intolerance to the drug occurs, it is better to consult with your doctor.

Like any potent drug, Nizoral has a number of contraindications for use:

• allergy to components;
• age up to 3 years;
• pregnancy and lactation;
• renal or liver failure;
• acute and chronic liver diseases;
• lactose intolerance;
• lactase deficiency;
• glucose-galactose malabsorption syndrome.

Nizoral tablets are not recommended for use in cases of low stomach acidity, adrenal insufficiency, or alcoholism. The product cannot be used simultaneously with the following drugs:

• medications that have a toxic effect on the liver;
• ergot alkaloids: methylergometrine, ergometrine, dihydroergotamine, ergotamine;
• eplerenone;
• everolimus;
• nisoldipine;
• irinotecan;
• HMG-CoA reductase inhibitors: lovastatin, simvastatin;
• substrates of the cytochrome P450 isoenzyme CYP3A4.

Ignoring contraindications can lead to the development of negative symptoms, so before using Nizoral in tablet form, you should consult your doctor.

Use during pregnancy

So far, it provides minimal information about how the drug affects the body of pregnant women and children who are in the womb. This topic has been little studied. However, during studies in which animals took part, a negative effect of the active components of the drug on their body was revealed. The degree of danger of Nizoral for humans has not yet been discovered.

Based on the data obtained, doctors do not recommend that pregnant women undergo treatment for fungal infections with Nizoral tablets. The only exceptions are those cases when the potential benefits of therapy outweigh the potential harm of the medication.

During treatment with Nizoral, women must refrain from breastfeeding.

Side effects

The use of Nizoral tablets can cause a number of negative side effects:

• headaches;
• general weakness;
• sleep disorders;
• anxiety, fatigue;
• abdominal pain, indigestion;
• liver dysfunction;
• decrease in pressure;
• gynecomastia;
• increased appetite;
• nosebleeds;
• myalgia;
• aversion to alcohol;
• disruption of the menstrual cycle in women;
• allergic rashes, itching, flushing;
• fever, chills.

Most of these side effects occurred in less than one percent of patients. If the recommended dosages are observed and the patient has no contraindications to the use of the drug, the likelihood of its occurrence is extremely low.

When applied, Nizoral ointment can cause irritation and, in rare cases, allergies. It also provokes hives, increased sensitivity, rashes and itching.

Using shampoo can cause the following negative reactions:

• increased skin sensitivity;
• irritation of treated skin;
• itching;
• rashes;
• irritation of the membranes of the eyes, increased tearing;
• change in taste perception;
• folliculitis;
• skin tightness;
• change in hair structure and color;

In case of an overdose of the drug, patients experience weakness, lethargy, nausea, diarrhea, rashes, increased sweating, and abdominal pain. To prevent further intoxication, you need to take activated charcoal and do a gastric lavage.

Side effects

Nizoral's ability to cause side effects was identified in 30 studies. About a thousand patients participated in the testing.

Itching, burning, swelling of the skin and erythema occur in more than 1% of subjects. They may occur due to applying the cream too often or applying too much medication.

Less than 0.1% of patients complained of the following negative phenomena:

• increased skin sensitivity,
• contact dermatitis,
• dryness, peeling of the epidermis,
• rashes,
• bullous rash,
• inflammatory process,
• bleeding,
• skin becomes sticky
• paresthesia.

The cream is prohibited for use in ophthalmic therapy.

The drug may cause irritation if used on the same area after long-term glucocorticoid drug therapy. If this happens, it is necessary to apply hormonal ointments in the mornings, and Nizoral in the evenings.

Drug interactions

Nizoral is incompatible with ethanol and enhances the toxic effect of diphenine. When used together with oral contraceptives, the drug increases the risk of bleeding. The drug also helps to increase the concentration of indirect anticoagulants, cyclosporine and methylprednisolone in the blood plasma.

The effectiveness of the active substance Nizoral is reduced when taken simultaneously with the following drugs:

• antacids;
• choline blockers;
• H2-histamine receptor blockers;
• rifampicin;
• isoniazid.

Only a specialist can select complex therapy for each patient so as to avoid the negative interaction of Nizoral with other drugs. In topical forms, the product has no drug interactions.

Analogs

Sebozol shampoo

Ketoconazole preparations are produced by many pharmaceutical companies. You can replace Nizoral shampoo with:

• Mycozoral (costs 300-400 rubles);
• Sebozol (140-240 rubles);
• Dandruff (480-550 rubles).

The most famous analogue of Nizoral ointment is Ketodin cream (price 170-240 rubles).

Analogues of tablets are the drugs Ketoconazole DS (pack of 10 tablets costs 210-240 rubles), Mycozoral (30 tablets - 490-530 rubles).

special instructions

If you have general weakness of the body, it is better not to use Nizoral.

Nizoral tablets have a toxic effect on the liver, so they should be used only in cases where local therapy does not have the desired effect, and the infectious agent is resistant to other types of antifungal agents.

Self-medication with this drug orally is unacceptable: therapy should be prescribed by a doctor, having first checked the functioning of the liver and ruled out the presence of chronic pathologies. During the course of treatment, it is necessary to constantly monitor the functioning of the liver and kidneys, monitor the condition of peripheral vessels, since even patients who are not at risk may develop toxic liver damage. For patients who have suffered intoxication or have elevated levels of liver enzymes, Nizoral is prescribed only in extreme cases, subject to strict control over liver functions.

If the following symptoms appear, you should immediately stop taking the drug and consult a doctor:

• nausea, vomiting;
• epigastric pain;
• general weakness;
• yellowing of the skin, sclera;
• darkening of urine;
• critical weight loss.

The absorption of the drug with reduced stomach acidity significantly worsens: to increase the absorption of the active substance, you can take it simultaneously with acidic drinks.

Reviews on treatment for lichen

If you want your hair to look beautiful and healthy, you need to take care of it.
At the first signs of skin diseases (dandruff, seborrhea, lichen, psoriasis), you should consult a doctor or consult a pharmacist who will help you choose a drug for treatment.

Choose only reliable products that you trust, pay attention to the composition. Only drugs with ketoconazole will help.

Irina

Imagine how dandruff ruins your life, and now imagine if you have shingles!
I picked up this nasty thing somewhere, from a cat. I was cured in a few sessions, I did everything as written in the instructions. Pleasant smell, for a cure for shingles.

Alla

My eldest son developed strange white spots that began to itch very much, our pediatrician sent us to the hospital, where they diagnosed lichen.
Read also: The best anti-dandruff shampoos in the pharmacy