We are glad to meet again with regular and new subscribers! The topic of the article today is the drug Metrogyl for demodicosis. Is it possible to use it in the fight against subcutaneous mites, and how to quickly achieve positive results?
Demodicosis is one of the skin diseases. Unlike pimples and comedones, which occur as a result of clogging of pores with sebum and dirt, the appearance of demodicosis is caused by a parasite.
The demodex mite, which can only be seen under high magnification under a microscope, lives on the body of more than half of people and animals. It may not manifest itself in any way for a long time, but under the influence of unfavorable factors (stress, weakened immunity, etc.) it becomes active and begins to declare itself:
- redness of the skin;
- inflammation;
- the appearance of a small rash;
- peeling and unpleasant itching.
Metrogyl gel: pharmacological properties
Metronidazole (1-(?-hydroxyethyl)-2-methyl-5-nitroimidazole) is an effective antibacterial and antiprotozoal agent from the group of nitroimidazole derivatives. Active against Trichomonas vaginalis, Entamoeba histolytica
and
Giardia intestinalis
, as well as for obligate anaerobes -
Bacteroides spp
.
( B. fragilis, B. distansonis, B. thetaiotaomicron, B. vulgatus), Fusobacterium spp., Clostridium spp., Peptostreptococcus spp., Peptococcus spp.
Inactive against aerobic microorganisms. The mechanism of action of Metrogyl is due to the biochemical reduction of the 5-nitro group of metronidazole by intracellular transport proteins of anaerobic microorganisms and protozoa. The reduced 5-nitro group of metronidazole interacts with the DNA of microorganisms, leading to their death. In the presence of mixed flora (aerobic and anaerobic bacteria), metronidazole acts synergistically with antibiotics active against aerobic microorganisms. Improvement usually occurs within 9 days of treatment.
How to use permethrin ointment for demodicosis?
Demodicosis is an unpleasant disease caused by demodex, a microscopic mite found in the sebaceous glands of various mammals, including humans.
With stress, metabolic disorders, and decreased immune status, the parasite begins to actively reproduce. As a result, the patient suffers from unpleasant rashes, itching, and the appearance of ulcers, and is quite naturally interested in how to get rid of this problem, what and how to use, how effective this or that remedy is. And it’s worth dwelling on such moments in more detail.
Treatment of demodicosis with ointments
Treatment for demodicosis is labor-intensive and lengthy; exact recommendations and time depend on the specific clinical picture, timely consultation with a doctor, and the body’s resistance. Everything can take up to a year.
Very often, doctors use an integrated approach: taking drugs internally is combined with external treatment.
The ointments help relieve itching, reduce or remove redness quite well:
- Ichthyol. Primarily relieves symptoms rather than cures.
- Benzyl benzoate is produced in various dosage forms, including as an ointment. An effective drug, but it causes allergies, so medical supervision is required. Now this product is being abandoned in favor of safer formulations.
- Sulfuric ointment. Prescribed for a variety of skin diseases. Kills ticks, accelerates skin healing. However, due to low efficiency and periodic occurrence of allergies, it is losing its position in the pharmacological market.
- Ointment Yam. It has a bactericidal effect, developed for animals, but approved for use in humans. It is difficult to wash off and has a strong unpleasant odor.
- Ornisol. Suppresses the action of microbes and parasites. May cause negative reactions in the body in case of individual intolerance.
There are now a large number of ointments of Chinese origin on the market. They are often presented as unique miracle drugs, but most of them are a combination of sulfur and herbal ingredients.
Treatment with permethrin ointment
One of the most effective products you can get on the market today is permethrin ointment. The main active components are pyrethroids, characterized by molecules of minimal size. The strength of the ointment was the deep penetration of particles through the patient’s skin, as well as through the tick’s shell. Thus, the composition kills parasites.
Laboratory studies have shown that permethrin ointment is more effective than sulfur ointment. At the same time, it does not accumulate in the body and has virtually no toxic effect on the skin.
Using this product is very simple: you need to apply it to the affected areas of the face and body in the evening, gently rubbing the product until it is absorbed. Do not rinse off, leave until morning. Be sure to clean the skin before treatment.
Before the first use, you should check if you have an allergic reaction. To do this, just anoint your wrist or elbow area and leave for half an hour. If there is no irritation, swelling, or redness, you can wash it off.
Results of using the ointment
Patients often wonder what sensations they should expect. Thus, reviews of permethrin ointment for demodicosis show that if the remedy begins to act (the diagnosis is correct), then within a few minutes the itching and burning sensation may intensify. This lasts up to half an hour, it is difficult to say more specifically, since much is individual and depends on how serious the damage to the body is in a particular case.
You can dilute the product with a plant-based baby cream.
Like all other drugs, permethrin ointment does not immediately help with demodicosis. You need to use it every day for a month, but noticeable improvement begins in the middle of the course, as a rule.
Contraindications and interactions with other medications
The product is not recommended for children under 3 years of age, pregnant women and nursing mothers. It is also worth considering individual negative reactions. In all other cases, the composition is safe.
Side effects are associated with an allergy to one of the components. Swelling, redness appear, burning and itching intensifies. In such a situation, the composition should be washed off immediately and consult a doctor. Most often they refuse to use this particular medicine.
As for the interaction, the drug is not combined with corticosteroids. Therefore, you need to stop taking them for the entire duration of the course in order to use the ointment. Otherwise, the likelihood of allergies increases and effectiveness decreases.
Question of price
The drug is most often ordered through online pharmacies because it is difficult to obtain in real pharmacies. And the price of permethrin ointment for demodicosis depends on the seller and the volume of the jar or tube. The most common options are 30 and 90 g. A little less often you can find containers of 50.
Thus, depending on the amount of product and the specific pharmacy, the cost ranges from 500 to 1000 rubles.
Reviews from people who used permethrin ointment
Permethrin ointment has been used for several years. And here's what former patients think about her:
Lisa, Moscow
At first I tried Yam... But that ointment turned out to be very nasty, it smelled unpleasant, there was a constant burning sensation. I didn’t like it, I decided that I needed to try something else. I contacted my doctor with a request to replace the substance for me. Well... In the end they changed it. I didn't notice any problems with rinsing. It didn’t stain my clothes, it only burned a little, but they told me that’s how it should be.
After 1.5 months everything went away. As I understand it, I was very lucky.
Olga, Krasnodar:
Hi all! My dermatologist asked me to write a review of permethrin ointment for demodicosis, he said that not everyone knows about it, but it treats much better than sulfur. Well, here I am writing, sharing, so to speak, my personal experience.
The ointment really helps much better, I have something to compare it with, because I had this disease in a very advanced form when I started using this particular drug.
As a result of sulfur, the skin became less red and inflamed, and the total number of rashes decreased. But very slowly, in some places it became less, and in others - more. The itching did not go away, the abscesses were still there.
After I started using permethrin, a lot has changed. At first it itched like hell, but then the rash began to go away, the itching stopped altogether, after 2 weeks I had to look closely to understand that I had something there! The doctor said that none of the more or less accessible ointments would give such an effect.
I can’t say that I recommend it to everyone, you still need to consult a doctor, and, well, allergies. But my personal experience has shown that this is really a good remedy.
Vlad Astafiev, Samara
Good ointment at a reasonable price, easy to use. Lubricate yourself in the evening and go for a walk. I put a jar near my bedside table, I come and smear myself. It's already automatic somehow. After about a month, everything seemed to go away. I still have the remedy left.
As you can see, permethrin ointment is not an ideal remedy; it has contraindications, and some people have allergies. But effective drugs are never 100% suitable for everyone. At the same time, the composition benefits from unique molecules that can penetrate deep into the skin, the absence of a strong odor and effectiveness.
In addition, it goes well with most other medications that are used in complex therapy.
Metrogyl gel: method of application
a thin layer of gel is applied to a previously cleansed affected area of skin 2 times a day (morning and evening) and lightly rubbed. A pronounced clinical effect occurs after 3 weeks of therapy.
Metrogyl gel: contraindications
hypersensitivity to metronidazole, other nitroimidazole derivatives and other components of the drug; I trimester of pregnancy and breastfeeding period.
Side effects
local reactions are possible - hyperemia, dry skin, burning sensation and skin irritation. When applied to the skin in the eye area, lacrimation may occur.
special instructions
Avoid getting the gel in your eyes. When applied to large areas of skin or with prolonged use, there is a possibility of resorption of metronidazole and the development of systemic side effects, so the drug should be prescribed with caution to patients with impaired hematopoietic function. If local reactions occur, the drug should be used less frequently or temporarily discontinued. Metronidazole penetrates well into breast milk, so it is not recommended to use Metrogyl during breastfeeding. After applying the gel, you can use cosmetics. During pregnancy, it is prescribed only if absolutely necessary.
Interactions
with external and intravaginal use of Metrogyl gel, an interaction due to systemic absorption of metronidazole is unlikely. However, when prescribing the drug to persons receiving anticoagulants, it should be remembered that metronidazole may enhance the anticoagulant effect of coumarin and warfarin, which leads to an increase in prothrombin time.
Overdose
no messages.
General information
The demodex mite parasitizes human skin, infecting the hair follicles of the head and eyelids. It begins to multiply rapidly under the influence of various factors: stress, unbalanced nutrition, tanning, hormonal changes in the body, and the use of fatty creams.
The production of sebum is stimulated, favorable conditions are created for the reproduction of the pathogenic organism, its waste products cause allergies and other symptoms:
- rash on the face, eyelids;
- itching, which intensifies in the evening and at night (the tick is most active at this time);
- rashes are localized in certain areas of the face with well-defined boundaries (erythematous form);
- papules and pustules of different colors against the background of hyperemia;
- hypertrophy of individual areas.
Demodectic mange of the scalp is manifested by itching and lumps on the skin.
Demodicosis of the eyes is manifested by a whitish border at the base of the eyelashes, inflammation of the edge of the eyelids. Without treatment it leads to conjunctivitis, blepharitis, keratitis and other dangerous ophthalmological diseases.
Contraindications for use
Do not use the product if you are hypersensitive to the active substance or other components in its composition.
The gel should not be used when treating children under 12 years of age. The dental type of medication is not recommended for children under 6 years of age.
The product is indicated for topical use in the treatment of acne that develops in adolescents during puberty, seborrhea, and rosacea that appear after hormonal treatment.
Instructions for use
Correct use of an antibacterial agent allows you to reduce the number of adult parasites, eliminate the unpleasant consequences of dermatological pathology in the form of acne and redness, and reduce the manifestations of the inflammatory process in the sebaceous glands.
How to take Metronidazole? Tablets of 250 mg should be taken 2 hours after breakfast and dinner, do not need to be chewed, and washed down with plenty of water. The medicine must be taken exactly at the same time, otherwise the effectiveness of therapy is noticeably reduced, and parasites can develop immunity to the active substances of the drug.
You cannot take a double dose at once, this is fraught with the occurrence of severe adverse reactions, even an overdose. Duration of therapy is 10 days. During this time, the condition of the skin improves noticeably, new acne does not appear, but sometimes a repeat course is required.
The regimen for taking external agents - gel or ointment should be used twice a day. The skin should be cleaned first, the medicine should be applied pointwise, affecting 2-3 cm of healthy epidermis - this will help prevent the movement of ticks.
The duration of therapy is 3–9 weeks, noticeable results will appear after 20 days of regular use. The medicine not only fights parasites, but also speeds up the regeneration process, reduces the likelihood of scars and scars appearing after acne disappears.
pharmachologic effect
Metronidazole is a synthetic imidazole derivative. Has a pronounced antimicrobial effect. In addition, it has an antiprotozoal effect against anaerobes and protozoan parasites. When used topically, it actively fights acne, preventing tissue damage in areas of inflammation. Has negligible antioxidant effectiveness. Does not work on telangiectasia or spider veins seen in rosacea.
Has minimal absorption. As a result of external use, traces of the drug may be detected in the blood serum. The absorbed substance penetrates the placenta and the blood-brain barrier.
Due to the high biological activity of the substance in the vaginal environment, the helium preparation is absorbed more efficiently than vaginal tablets. Even with a minimal concentration of the active component, a therapeutic effect is observed. This reduces the likelihood of side effects.
Antibiotic therapy
It will not be possible to cure demodicosis without antibacterial drugs . A doctor must prescribe the medicine; self-medication can lead to serious complications and progression of the disease. Moreover, the patient himself will not be able to assess the effectiveness of therapy and the combination of medications.
The most popular antibiotic is Metronidazole and its analogue Trichopolum. Whether the drug helps against demodicosis - the result of treatment depends on the severity of the disease and the patient’s compliance with the doctor’s recommendations. In addition to the treatment of skin parasites (mites), Metronidazole is an effective remedy against malaria, hormonal acne and other pathologies.
Regimen for taking Metronidazole for demodicosis : twice a day, one capsule for 10–15 days. The tablets should be taken immediately after meals with plenty of water.
The advantage of Metranidazole is its affordable cost and different forms of release - tablets, gel or vaginal suppositories. You can use the tablet and local form of the drug at the same time. Due to its broad spectrum of action, Metranidazole has a rapid therapeutic effect.
Treatment of demodicosis with Metronidazole involves complete abstinence from drinking alcoholic beverages. Even a small dose of alcohol can cause unwanted effects.
I used it to treat demodicosis: powerful, effective, but a bad side effect
The very first dermatologist to whom I turned for help, having fallen ill with demodicosis, prescribed me, in addition to many external remedies, physiotherapy and some injections, the antibiotic metronidazole, familiar to many. Many “experienced” people will now object: they say, metronidazole does not kill demodex! Yes, you are absolutely right, but this drug perfectly kills other microorganisms that usually accompany the vigorous life of a tick under your skin during demodicosis. For alone this insect is unable to cause as much trouble as occurs in the acute stage of the disease. So, my diagnosis was: “Rosacea complicated by demodicosis.”
In other words, metronidazole inside, like Metrogyl gel or Rosamet cream outside, helps kill those harmful microorganisms that, in the nutrient medium formed by tick waste, begin to develop rapidly and provoke those terrible redness and huge ulcers that are sometimes almost impossible to even squeeze out .
I took Metronidazole according to a terrible regimen: 10 days, 4 tablets per day. Then 10 days - 3 tablets each and another 10 days - 2 tablets each. Result: demodicosis was cured, but the liver began to fly away with terrible force - I lost my appetite, and often felt sick. I started taking Liv 52 only in the middle of treatment with metronidazole (doctor’s negligence - I forgot to prescribe a hepatoprotector), and it really helped me restore my liver. Then she also took the probiotic Liveo 4, because constipation, flatulence and other signs of dysbiosis appeared after taking antibiotics.
Rules for treating demodicosis with Metronidazole
The dosage of Metronidazole in the treatment of demodicosis, as well as its duration, is determined by the doctor. It is prohibited to use the drug in a higher dosage or independently increase (decrease) the duration of therapy. This can cause complications and adverse reactions.
Taking Metronidazole for demodicosis should be carried out strictly according to the schedule. Skipping the next dose increases the risk of infection progression and development of parasite tolerance to the antibiotic. The missed pill should be taken as soon as possible. However, you should not take two tablets at once. This provokes dyspeptic disorders - nausea, vomiting, stool disorders.
Contraindications and side effects
Metronidazole is a strong antibiotic, so it has a number of restrictions for use; some negative reactions may occur during treatment.
Possible side effects:
- dyspeptic disorders - diarrhea or constipation, nausea, loss of appetite, colic, sometimes severe thirst, exacerbation of pancreatitis, stomatitis;
- disturbances in the functioning of the central nervous system - attacks of dizziness, problems with coordination, depression, irritability, headache, insomnia;
- allergic reactions in the form of rash, redness of the skin, itching;
- disruption of the urination process, sometimes the urine turns red-brown;
- thrombophlebitis.
The video is dedicated to the treatment of tick-borne acne with antimicrobial drugs:
The drug is not prescribed for hypersensitivity, intolerance to the ingredients of the drug in nursing women, patients with a history of epilepsy, leukopenia.
The video provides detailed information about the features of Metronidazole:
The medicine should be taken under constant medical supervision during pregnancy, in the presence of liver and kidney failure.
Metronidazole helps to quickly cope with the manifestations of demodicosis and has a detrimental effect on the causative agents of dermatological pathology. The drug is a strong antibiotic, so before starting treatment you should carefully study the instructions and do not exceed the recommended dosage.
The effectiveness of sulfur ointment and its medicinal properties
Sulfur ointment is a product that has disinfecting and anti-inflammatory properties. This drug fights fungal infections well and restores damaged areas of the skin. This remedy has become a real discovery in the fight against skin diseases.
More than a century ago, people fought their ailments with the help of tar, iodine and sulfur. The discovery of sulfur ointment made it possible to obtain an effective remedy in a form convenient for use and storage. Its production is based on the “Deryagin rule,” which is still popular in pharmaceutical companies today. The medicinal substance (sulfur) is ground dry and added to a solvent (vaseline). The mass of such should be 2 times less than the mass of the active element itself. The initial recipe for the miraculous ointment has undergone some changes.
There is less sulfur in the medicine. Often used ointment with 8, 10 and 33% of its content. Such actions were necessary due to the toxicity of the drug used.
Sulfur ointment for demodicosis can be used even during pregnancy, despite its pungent odor. This tool is called multidisciplinary. With its help you can get rid of:
- demodicosis,
- scabies,
- seborrheic dermatitis,
- fungal infections,
- pityriasis rosea,
- psoriasis,
- acne,
- lice.
The properties of sulfur ointment can be called miraculous and multidisciplinary. Although the instructions for the drug indicate only 4 diseases that the drug can overcome.
Sulfur ointment can also remove lice
